Pharmaceutical Development

Pre-formulation

At LEF each drug and excipient goes through a customized pre-formulation characterization to identify the best formulation strategy for each product.

  •  Pre-formulation
  •  Solubility/permeability and stability evaluation
  •  Comprehensive excipient screening
Formulation development and Production
Each product is unique. At our pilot plant unit, the integration of pre-formulation data with a careful formulation development plan will allow the efficient development of robust, easily manufacturable drug products.
 
Flexibility is crucial. We are prepared to produce small batches of non sterile solid, semi-solids and liquid dosage forms, including clinical supplies for clinical trials, under full cGMP conditions.
  • Prototype Development
  • Formulation Optimization
  • Pilot scale manufacturing of non sterile solid, semi-solids and liquid dosage forms
  • Biobatch manufacturing and clinical supplies
  • Scale up support
  • Full data documentation
Throughout the development process a close collaboration is maintained with our clients. Emphasis is put on providing all the relevant information at each developing step. Our goal is to achieve a final dosage form that ensures patient compliance and our customers corporate objectives.

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